OPA1 Antibody

• Description:

  Dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis. May form a diffusion barrier for proteins stored in mitochondrial cristae. Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space.

• Specifications:

  Western blot: 1:500-1:2000

• UniProt:

  O60313

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A synthetic peptide specific to human OPA1 was used as the immunogen for the OPA1 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG

• Clone:

  ACGD-15

• Type:

  Recombinant

• Applications:

  WB

• Purity:

  Affinity purified

• Format:

  Purified

• Buffer:

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

• Reconstitution:

  Store the OPA1 antibody at -20oC.

• Limitations:

  This OPA1 antibody is available for research use only.

• Storage Conditions:

  Store the OPA1 antibody at -20°C.

• Formulation:

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

• Applications Notes:

  Optimal dilution of the OPA1 antibody should be determined by the researcher.

• CAS Number:

  9000-83-3

• Image Legend:

  Western blot testing of human HeLa cell lysate with OPA1 antibody. Predicted molecular weight: 111-120 kDa with multiple smaller isoforms from 81-95 kDa.