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Phospho-FOXO3A Antibody

CAT: 0800-RQ4742Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0800-RQ4742Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FOXO3 is a transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. [UniProt]
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
O43524
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human FOXO3A (surrounding pS253) was used as the immunogen for the phospho-FOXO3A antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
ECG-6
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the phospho-FOXO3A antibody at -20oC.
Limitations
This phospho-FOXO3A antibody is available for research use only.
Storage Conditions
Store the phospho-FOXO3A antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the phospho-FOXO3A antibody should be determined by the researcher.
Image Legend
Western blot testing of IGF-treated human MCF-7 lysate with phospho-FOXO3A antibody. Expected molecular weight: 71-90 kDa depending on glycosylation level.

UniProtKB · O43524

Forkhead box protein O3

FOXO3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O43524
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FOXO3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B4DVZ6, E1P5E6, O15171, Q5T2I7, Q9BZ04
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationMethylationPhosphoproteinUbl conjugation

Molecular function

ActivatorDNA-binding

Coding sequence diversity

Alternative splicingChromosomal rearrangement

Biological process

ApoptosisTranscriptionTranscription regulation

Cellular component

CytoplasmMembraneMitochondrionMitochondrion outer membraneNucleus

Disease

Proto-oncogene

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