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P73 Antibody

CAT: 0800-RQ4726Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0800-RQ4726Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The TP73 encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [RefSeq]
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:50-1:200
UniProt
O15350
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide specific to human p73 / TP73 was used as the immunogen for the p73 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
EHI-20
Type
Recombinant
Applications
WB, IHC-P
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the p73 antibody at -20oC.
Limitations
This p73 antibody is available for research use only.
Storage Conditions
Store the p73 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the p73 antibody should be determined by the researcher.
Image Legend
IHC staining of FFPE mouse brain tissue with p73 antibody, HRP-labeled secondary and DAB substrate. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
Product Datasheet
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