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HEC1 Antibody / NDC80

CAT: 0800-RQ4712Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0800-RQ4712Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.
CAS Number
9000-83-3
Specifications
Western blot: 1:1000-1:5000
UniProt
O14777
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide specific to human HEC1 / NDC80 was used as the immunogen for the HEC1 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
ACBI-14
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the HEC1 antibody at -20oC.
Limitations
This HEC1 antibody is available for research use only.
Storage Conditions
Store the HEC1 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the HEC1 antibody should be determined by the researcher.
Image Legend
Western blot testing of human Jurkat cell lysate with HEC1 antibody. Expected molecular weight: 74-80 kDa.

UniProtKB · O14777

Kinetochore protein NDC80 homolog

NDC80_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O14777
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NDC80
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q6PJX2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Biological process

Cell cycleCell divisionMitosis

Cellular component

CentromereChromosomeKinetochoreNucleus

Domain

Coiled coil
Product Datasheet
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