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DR5 Antibody

CAT: 0800-RQ4711Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0800-RQ4711Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The protein encoded by the TNFRSF10B is a member of the TNF-receptor superfamily, and contains an intracellular death domain. Death receptor 5 can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [RefSeq]
CAS Number
9000-83-3
Specifications
Western blot: 1:1000-1:5000
UniProt
O14763
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human DR5 / TNFRSF10B was used as the immunogen for the DR5 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
ABFC-20
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the DR5 antibody at -20oC.
Limitations
This DR5 antibody is available for research use only.
Storage Conditions
Store the DR5 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the DR5 antibody should be determined by the researcher.
Image Legend
Western blot testing of human HeLa cell lysate with DR5 antibody. Expected molecular weight: ~40 kDa (mature form) and ~48 kDa (precursor) . This protein may also be visualized at ~60 kDa.

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