IL22 Antibody

CAT: 0800-RQ4626Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-RQ4626Size:100 µg
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Description
Interleukin-22 (IL-22), also known as ILTIF, is protein that in humans is encoded by the IL22 gene. IL-22 a member of a group of cytokines called the IL-10 family or IL-10 superfamily, a class of potent mediators of cellular inflammatory responses. Using FISH, the IL22 gene is mapped to chromosome 12q15, close to the IFNG and the herpesvirus saimiri-induced AK155 genes. IL-22 can contribute to immune disease through the stimulation of inflammatory responses, S100s and defensins. It also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10. In some contexts, the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by the often co-expressed cytokine IL-17A.
CAS Number
9007-83-4
Specifications
FACS: 1-3ug/10^6 cells
UniProt
Q9GZX6
Host
Mouse
Reactivity
Human
Immunogen
Amino acids A34-I179 from the human protein were used as the immunogen for the IL22 antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
7F2
Applications
FACS
Purity
Protein G affinity
Format
Purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the IL22 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Storage Conditions
After reconstitution, the IL22 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the IL22 antibody should be determined by the researcher.
Image Legend
Flow cytometry testing of human HL60 cells with IL22 antibody at 1ug/10^6 cells (blocked with goat sera) ; Red=cells alone, Green=isotype control, Blue= IL22 antibody.

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