IFNAR1 Recombinant Antibody / Interferon alpha receptor 1

• Description:

  Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves. Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). [UniProt]

• UniProt:

  P17181

• Host:

  Rabbit

• Immunogen:

  A synthetic peptide from human Interferon Receptor alpha was used as the immunogen for the IFNAR1 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG

• Type:

  Recombinant

• Applications:

  WB

• Format:

  Purified

• Buffer:

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

• Reconstitution:

  Store the IFNAR1 antibody at -20oC.

• Limitations:

  This IFNAR1 antibody is available for research use only.

• CAS Number:

  9000-83-3