IFNAR1 Recombinant Antibody / Interferon alpha receptor 1

IFNAR1 Recombinant Antibody / Interferon alpha receptor 1

• Description: Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves. Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). [UniProt]
• CAS Number: 9000-83-3
• UniProt: P17181
• Host: Rabbit
• Immunogen: A synthetic peptide from human Interferon Receptor alpha was used as the immunogen for the IFNAR1 antibody.
• Clonality: Monoclonal
• Isotype: IgG
• Type: Recombinant
• Applications: WB
• Format: Purified
• Buffer: Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
• Reconstitution: Store the IFNAR1 antibody at -20oC.
• Limitations: This IFNAR1 antibody is available for research use only.