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RANK Antibody

CAT: 0800-RQ4403Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ4403Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells. [UniProt]
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Direct ELISA: 0.1-0.5 µg/mL (recombinant human protein) (BSA-free format available)
UniProt
Q9Y6Q6
Host
Rabbit
Reactivity
Human
Immunogen
A human partial recombinant protein corresponding to amino acids C34-L211 was used as the immunogen for the RANK antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the RANK antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This RANK antibody is available for research use only.
Storage Conditions
After reconstitution, the RANK antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the RANK antibody should be determined by the researcher.
Image Legend
Western blot testing of human 1) HeLa, 2) placenta, 3) MCF7 and 4) SK-OV-3 lysate with RANK antibody at 0.5ug/ml. Predicted molecular weight ~66 kDa, routinely observed at 80~100 kDa.

UniProtKB · Q9Y6Q6

Tumor necrosis factor receptor superfamily member 11A

TNR11_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y6Q6
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TNFRSF11A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
I4EC36, I4EC38, I4EC39, I7JE63, N0GVH0, Q59EP9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembrane

Disease

DeafnessDisease variantOsteopetrosis

PTM

Disulfide bondGlycoproteinPhosphoprotein

Ligand

Metal-bindingSodium

Molecular function

Receptor

Domain

RepeatSignalTransmembraneTransmembrane helix
Product Datasheet
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