Products for Research Use Only
RegisterLogin

GFI1 Antibody

CAT: 0800-RQ4261Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-RQ4261Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Zinc finger protein Gfi-1 is a protein that in humans is encoded by the GFI1 gene. This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.
CAS Number
9007-83-4
Specifications
IHC (FFPE) : 1-2 µg/mL
UniProt
Q99684
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids NLITHSRKHTGFKPFGCDLCGKGFQRKVDLRRHRETQH were used as the immunogen for the GFI1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
IHC-P
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the GFI1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This GFI1 antibody is available for research use only.
Storage Conditions
After reconstitution, the GFI1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the GFI1 antibody should be determined by the researcher.
Location
Nucleus
Image Legend
IHC testing of FFPE human breast cancer tissue with GFI1 antibody at 1ug/ml. Required HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.

Related Products

CatalogName
RQ4624NONO Antibody / p54nrb Antibody
F53954-0.05MLAntibody
F53954-0.2MLAntibody
F53952-0.2MLAntibody
F53952-0.05MLAntibody
V8674-20UGInhibin alpha Antibody / INHA antibody
V8674SAF-100UGInhibin alpha Antibody / INHA antibody
V8674-100UGInhibin alpha Antibody / INHA antibody
R20161SAF-250UGLambda Light Chain Antibody / Lambda Antibody
R30971B-Actin Antibody / Beta Actin Antibody

Alternative Products

CatalogName
GTR18148287GFI1 Antibody

Popular Products