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TPX2 Antibody

CAT: 0800-RQ4199Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ4199Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Targeting protein for Xklp2, also known as C20ORF1, is a protein that in humans is encoded by the TPX2 gene. It is mapped to chromosome 20q11.2. It was concluded that even in the presence of duplicated centrosomes, spindle formation requires the function of TPX2 to generate a stable bipolar spindle with overlapping antiparallel microtubule arrays. At the onset of mitosis, GOLGA2 interacts with importin-alpha, liberating TPX2 from importin-alpha, allowing TPX2 to activates AURKA kinase and stimulates local microtubule nucleation.
CAS Number
9007-83-4
Specifications
Western Blot: 0.5-1 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q9ULW0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A recombinant human protein corresponding to amino acids D15-Q93 was used as the immunogen for the TPX2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the TPX2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This TPX2 antibody is available for research use only.
Storage Conditions
After reconstitution, the TPX2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the TPX2 antibody should be determined by the researcher.
Image Legend
Western blot testing of human 1) HeLa, 2) COLO320, 3) U-87 MG, 4) SGC-7901, 5) rat PC-12 and 6) mouse HEPA1-6 lysate with TPX2 antibody at 0.5ug/ml. Predicted molecular weight ~86 kDa, observed at ~100 kDa.

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