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APOBEC3A Antibody / PHO1

CAT: 0800-RQ4184Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ4184Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A, also known as APOBEC3A, is a gene of the APOBEC3 family found in humans, non-human primates, and some other mammals. This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22.The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Specifications
Western Blot: 0.5-1 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P31941
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A recombinant human protein corresponding to amino acids M1-L63 was used as the immunogen for the APOBEC3A antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the APOBEC3A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This APOBEC3A antibody is available for research use only.
Storage Conditions
After reconstitution, the APOBEC3A antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the APOBEC3A antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) human HeLa, 2) human Caco-2, 3) human A549, 4) rat PC-12 and 5) mouse RAW264.7 cell lysate with APOBEC3A antibody. Predicted molecular weight ~23 kDa.

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