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IL-27 Antibody / Alpha Subunit

CAT: 0800-RQ4175Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ4175Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Interleukin 27 (IL-27) is a member of the IL-12 cytokine family. The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A) . It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4 (+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4 (+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR) .
CAS Number
9007-83-4
Specifications
Western Blot: 0.5-1 µg/mL, ELISA (Capture) : 0.1-0.5 µg/mL
UniProt
Q8NEV9
Host
Rabbit
Reactivity
Human
Immunogen
A recombinant human protein corresponding to amino acids F29-P243 was used as the immunogen for the IL-27 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the IL-27 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This IL-27 antibody is available for research use only.
Storage Conditions
After reconstitution, the IL-27 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the IL-27 antibody should be determined by the researcher.
Image Legend
Western blot testing of human CCRF-CEM cell lysate with IL-27 antibody at 0.5ug/ml. Predicted molecular weight ~28 kDa, observed here at ~20 kDa.
Product Datasheet
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Alternative Products

CatalogName
397453IL27 (Interleukin-27 Subunit Alpha, IL-27 Subunit Alpha, IL-27-A, IL27-A, p28, Il27a)
128456IL27 (Interleukin-27 Subunit alpha, IL-27 Subunit alpha, IL-27-A, IL27-A, p28, IL27A, MGC71873)
146084IL27, NT (Interleukin-27 Subunit alpha, IL-27 Subunit alpha, IL-27-A, IL27-A, p28, IL27A)
146085IL27, ID (Interleukin-27 Subunit alpha, IL-27 Subunit alpha, IL-27-A, IL27-A, p28, IL27A)
128455-APCIL27 (Interleukin-27 Subunit alpha, IL-27 Subunit alpha, IL-27-A, IL27-A, p28, IL27A, MGC71873) (APC)
128455-HRPIL27 (Interleukin-27 Subunit alpha, IL-27 Subunit alpha, IL-27-A, IL27-A, p28, IL27A, MGC71873) (HRP)
128455-FITCIL27 (Interleukin-27 Subunit alpha, IL-27 Subunit alpha, IL-27-A, IL27-A, p28, IL27A, MGC71873) (FITC)
128456-PEIL27 (Interleukin-27 Subunit alpha, IL-27 Subunit alpha, IL-27-A, IL27-A, p28, IL27A, MGC71873) (PE)
128456-BiotinIL27 (Interleukin-27 Subunit alpha, IL-27 Subunit alpha, IL-27-A, IL27-A, p28, IL27A, MGC71873) (Biotin)
147005IL27, Control Peptide (Interleukin-27 Subunit alpha, IL-27 Subunit alpha, IL-27-A, IL27-A, p28, IL27A)

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