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ICOS Antibody

CAT: 0800-RQ4163Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ4163Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Inducible T-cell costimulator is an immune checkpoint protein that in humans is encoded by the ICOS gene. The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.
CAS Number
9007-83-4
Specifications
IHC (FFPE) : 1-2 µg/mL, Direct ELISA: 0.1-0.5 µg/mL, FACS: 1-3ug/10^6 cells
UniProt
Q9Y6W8
Host
Rabbit
Reactivity
Human
Immunogen
A recombinant human protein corresponding to amino acids E21-K140 was used as the immunogen for the ICOS antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
FACS, IHC-P, ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the ICOS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This ICOS antibody is available for research use only.
Storage Conditions
After reconstitution, the ICOS antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the ICOS antibody should be determined by the researcher.
Location
Cytoplasmic, cell membrane
Image Legend
IHC testing of FFPE human tonsil tissue with ICOS antibody at 1ug/ml. Required HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.

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