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IL-4 Antibody

CAT: 0800-RQ4162Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ4162Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Interleukin-4 (IL-4), also known as a B-cell stimulatory factor1 (BSF1), is an immunomodulatory cytokine, which can inhibit the growth of tumour cells.1 The human cDNA contains a single open reading frame encoding a protein of 153 amino acids, including a putative signal peptide. IL-4 may act as an autocrine growth factor in pancreatic cancer cells and also give rise to the possibility that cancer-derived IL-4 may suppress cancer-directed immunosurveillance in vivo in addition to its growth-promoting effects, thereby facilitating pancreatic tumor growth and metastasis. The mouse and human genes and their protein products show structural and functional similarities.
CAS Number
9007-83-4
Specifications
Western Blot: 0.5-1 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P05112
Host
Rabbit
Reactivity
Human
Immunogen
A recombinant human protein corresponding to amino acids H25-S153 was used as the immunogen for the IL-4 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the IL-4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This IL-4 antibody is available for research use only.
Storage Conditions
After reconstitution, the IL-4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the IL-4 antibody should be determined by the researcher.
Image Legend
Western blot testing of human CCRF-CEM cell lysate with IL-4 antibody at 0.5ug/ml. Expected molecular weight: 14-20 kDa depending on glycosylation level.
Product Datasheet
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