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Pai-1 Antibody

CAT: 0800-RQ4041Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ4041Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Plasminogen activator inhibitor-1 (PAI-1) also known as endothelial plasminogen activator inhibitoror serpin E1 is a protein that in humans is encoded by the SERPINE1 gene. This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Specifications
Western Blot: 0.5-1 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P20961
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
A recombinant rat partial protein corresponding to amino acids S24-D240 was used as the immunogen for the Pai-1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the Pai-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Pai-1 antibody is available for research use only.
Storage Conditions
After reconstitution, the Pai-1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Pai-1 antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) rat small intestine, 2) rat kidney and 3) mouse kidney lysate with Pai-1 antibody at 0.5ug/ml. Predicted molecular weight ~45 kDa.

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