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AGRP Antibody

CAT: 0800-RQ4011Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ4011Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Agouti-related protein (AgRP), also called agouti-related peptide, is a neuropeptide produced in the brain by the AgRP/NPY neuron. In humans, the agouti-related peptide is encoded by the AGRP gene. This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.
CAS Number
9007-83-4
Specifications
IHC (FFPE) : 1-2 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P56473
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A recombinant mouse partial protein corresponding to amino acids S82-T131 was used as the immunogen for the AGRP antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
IHC-P, ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the AGRP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This AGRP antibody is available for research use only.
Storage Conditions
After reconstitution, the AGRP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the AGRP antibody should be determined by the researcher.
Location
Cytoplasmic, secreted
Image Legend
IHC testing of FFPE mouse lung tissue with AGRP antibody at 1ug/ml. Required HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to testing.
Product Datasheet
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