Azenosertib

CAT: 0804-HY-132295-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-132295-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Azenosertib (ZN-c3) is a selective, orally active inhibitor for Wee1 inhibitor (IC50=3.9 nM) . Azenosertib exhibits antitumor activity[1].
CAS Number
[2376146-48-2]
Product Name Alternative
ZN-c3
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Wee1
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/zn-c3.html
Purity
99.96
Solubility
DMSO : 175 mg/mL (ultrasonic)
Smiles
O=C1N(CC=C)N(C2=CC=C(CC[C@@]3(CC)O)C3=N2)C4=NC(NC5=CC=C(N6CCN(C)CC6)C=C5)=NC=C41
Molecular Formula
C29H34N8O2
Molecular Weight
526.63
Precautions
H302, H315, H319
References & Citations
[1]Huang PQ, et al. Discovery of ZN-c3, a Highly Potent and Selective Wee1 Inhibitor Undergoing Evaluation in Clinical Trials for the Treatment of Cancer [published online ahead of print, 2021 Aug 23]. J Med Chem. 2021;10.1021/acs.jmedchem.1c01121.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

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