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CD105 Antibody

CAT: 0800-R32935Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32935Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Endoglin (Osler-Rendu-Weber syndrome 1), CD105, is a type I membrane glycoprotein located on cell surfaces and is a part of the TGF beta receptor complex. Its gene is mapped to human chromosome 8. The protein consists of a homodimer of 180 kDA with disulfide links. It has been found on endothelial cells, activated macrophages, fibroblasts and smooth muscle cells. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling and has been found to be elevated in pregnant women who subsequently develop preeclampsia.
CAS Number
9007-83-4
Specifications
Western Blot: 0.5-1 µg/mL, IHC (FFPE) : 1-2 µg/mL, Direct ELISA (recombinant mouse protein) : 0.1-0.5 µg/mL (BSA-free format available)
UniProt
Q63961
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
A recombinant mouse protein corresponding to amino acids E27-L226 was used as the immunogen for the CD105 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, Direct ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
Reconstitution
After reconstitution, the CD105 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This CD105 antibody is available for research use only.
Storage Conditions
After reconstitution, the CD105 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the CD105 antibody should be determined by the researcher.
Location
Cell surface, cytoplasmic
Image Legend
IHC testing of FFPE mouse kidney tissue with CD105 antibody at 1ug/ml. Required HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to testing.

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