IL22 Antibody

• Description :

  Interleukin-22 (IL22), also known as ILTIF, is protein that in humans is encoded by the IL22 gene. IL-22 a member of a group of cytokines called the IL-10 family or IL-10 superfamily, a class of potent mediators of cellular inflammatory responses. Using FISH, the IL22 gene is mapped to chromosome 12q15, close to the IFNG and the herpesvirus saimiri-induced AK155 genes. IL-22 can contribute to immune disease through the stimulation of inflammatory responses, S100s and defensins. It also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10. In some contexts, the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by the often co-expressed cytokine IL-17A.

• Specifications :

  Western Blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, ELISA (human recombinant protein) : 0.1-0.5 µg/mL (BSA-free format available)

• UniProt :

  Q9GZX6

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A recombinant human protein corresponding to amino acids A34-I179 was used as the immunogen for the IL22 antibody.

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  WB, ELISA

• Purity :

  Antigen affinity

• Format :

  Antigen affinity purified

• Buffer :

  Lyophilized from 1X PBS with 2% Trehalose

• Reconstitution :

  After reconstitution, the IL22 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

• Limitations :

  This IL22 antibody is available for research use only.

• Storage Conditions :

  After reconstitution, the IL22 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

• Formulation :

  0.5 mg/mL if reconstituted with 0.2ml sterile DI water

• Applications Notes :

  Optimal dilution of the IL22 antibody should be determined by the researcher.

• CAS Number :

  9007-83-4

• Location :

  Secreted

• Image Legend :

  IHC staining of FFPE human spleen tissue with IL22 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.