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IGFBP3 Antibody

CAT: 0800-R32836Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32836Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IGFBP3, Insulin-like growth fator-binding protein 3, is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. IGFBP3 is located on chromosome 7. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
CAS Number
9007-83-4
Specifications
Western Blot: 0.5-1 µg/mL, ELISA (Capture; human recombinant protein) : 0.1-0.5 µg/mL (BSA-free formulation available)
UniProt
P17936
Host
Rabbit
Reactivity
Human
Immunogen
A recombinant human protein corresponding to amino acids A29-K267 was used as the immunogen for the IGFBP3 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, ELISA (capture)
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
Reconstitution
After reconstitution, the IGFBP3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This IGFBP3 antibody is available for research use only.
Storage Conditions
After reconstitution, the IGFBP3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the IGFBP3 antibody should be determined by the researcher.
Location
Secreted
Image Legend
Western blot testing of recombinant human protein with IGFBP3 antibody at 0.5ug/ml. Expected molecular weight: ~31/40-44 kDa (unmodified/glycosylated) .
Product Datasheet
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