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BRMS1 Antibody

CAT: 0800-R32791Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32791Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Breast cancer metastasis-suppressor 1 is a protein that in humans is encoded by the BRMS1 gene. This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC) . The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
Q9HCU9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids D52-D244 from the human protein were used as the immunogen for the BRMS1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
Reconstitution
After reconstitution, the BRMS1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This BRMS1 antibody is available for research use only.
Storage Conditions
After reconstitution, the BRMS1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the BRMS1 antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) rat kidney, 2) rat liver, 3) mouse liver and 4) human HeLa lysate with BRMS1 antibody at 0.5ug/ml. Predicted molecular weight ~28 kDa, often observed at ~35 kDa.

UniProtKB · Q9HCU9

Breast cancer metastasis-suppressor 1

BRMS1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9HCU9
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BRMS1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q6IAI2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

ApoptosisTranscriptionTranscription regulation

Domain

Coiled coil

Cellular component

CytoplasmNucleus

PTM

Isopeptide bondUbl conjugation

Molecular function

Repressor

Disease

Tumor suppressor

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GWB-MX034GBRMS1 Antibody

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