Products for Research Use Only
RegisterLogin

Cytoglobin Antibody

CAT: 0800-R32779Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-R32779Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Cytoglobin (CYGB), also called HGB or STAP, is a ubiquitously expressed hexacoordinate hemoglobin that may facilitate diffusion of oxygen through tissues, scavenge nitric oxide or other reactive oxygen species, or serve a protective function during oxidative stress. The cytoglobin gene is mapped on 17q25.1. The CYGB gene contains 4 exons and spans about 9 kb. Cytoglobin has many elements common to vertebrate globins, including invariant histidine residues, and the amino acids that form the heme pocket share similarity with pentacoordinate myoglobin. In contrast to the high oxygen affinities displayed by most hexacoordinate hemoglobins, the characteristics of CYGB indicate that it can facilitate oxygen transport. Because the oxygen affinity of CYGB is more similar to myoglobin than to neuroglobin, and the oxy form of CYGB resists autooxidation, CYGB is proposed to represent a tissue oxygen reservoir.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 1-2 µg/mL
UniProt
Q8WWM9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids M1-P190 from the human protein were used as the immunogen for the Cytoglobin antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
Reconstitution
After reconstitution, the Cytoglobin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Cytoglobin antibody is available for research use only.
Storage Conditions
After reconstitution, the Cytoglobin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Cytoglobin antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
IHC testing of FFPE human intestinal cancer tissue with Cytoglobin antibody at 1ug/ml. Required HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to testing.

UniProtKB · Q8WWM9

Cytoglobin

CYGB_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8WWM9
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CYGB
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q541Y7, Q8N2X5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

CytoplasmNucleus

PTM

Disulfide bond

Ligand

HemeIronMetal-binding

Molecular function

Oxidoreductase

Related Products

CatalogName
RQ4624NONO Antibody / p54nrb Antibody
F53954-0.05MLAntibody
F53954-0.2MLAntibody
F53952-0.2MLAntibody
F53952-0.05MLAntibody
V8674-20UGInhibin alpha Antibody / INHA antibody
V8674SAF-100UGInhibin alpha Antibody / INHA antibody
V8674-100UGInhibin alpha Antibody / INHA antibody
R20161SAF-250UGLambda Light Chain Antibody / Lambda Antibody
R30971B-Actin Antibody / Beta Actin Antibody

Alternative Products

CatalogName
70R-14194Cytoglobin antibody
JOT-AP08335-01Cytoglobin Polyclonal Antibody
MBS178639-01Anti-Cytoglobin Antibody
abx128188-01Cytoglobin (CYGB) Antibody
GTR19017092-01Cytoglobin

Popular Products