Products for Research Use Only

FDCSP Antibody

CAT: 0800-R32777Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32777Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FDC-SP or follicular dendritic cell-secreted protein, is a small, secreted protein, located on chromosome 4 in humans. FDC-SP is a 68-amino acid protein containing a signal peptide at its N terminus, which is used for directing the transport of the protein. This protein specifically binds to activated B cells, and functions as a regulator of antibody responses. It is also thought to contribute to tumor metastases by promoting cancer cell migration and invasion.
CAS Number
9007-83-4
Specifications
Immunhistochemistry (FFPE) : 1-2 µg/mL, Immunofluorsecence (FFPE) : 5 µg/mL
UniProt
Q8NFU4
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids 18-51 (FPVSQDQEREKRSISDSDELASGFFVFPYPYPFR) from the human protein were used as the immunogen for the FDCSP antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
IHC-P, IF
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the FDCSP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This FDCSP antibody is available for research use only.
Storage Conditions
After reconstitution, the FDCSP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the FDCSP antibody should be determined by the researcher.
Location
Cytoplasmic, membranous, secreted
Image Legend
Immunofluorescent staining of FFPE human tonsil tissue with FDCSP antibody (green) and DAPI nuclear stain (blue) . HIER: steam section in pH8 EDTA buffer for 20 min.

UniProtKB · Q8NFU4

Follicular dendritic cell secreted peptide

FDSCP_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8NFU4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FDCSP
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
FDC secreted protein, FDC-SP
EC number
—
Processing
Precursor
Secondary accessions
—
Protein keywords

PTM

Glycoprotein

Technical term

Proteomics identificationReference proteome

Cellular component

Secreted

Domain

Signal