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TRAIL Antibody

CAT: 0800-R32732Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32732Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TNF-related apoptosis-inducing ligand (TRAIL), is a protein functioning as a ligand that induces the process of cell death called apoptosis. TRAIL has also been designated CD253 (cluster of differentiation 253) . It is a member of Tumor Necrosis Factor Ligand Superfamily. In humans, the gene that encodes for TRAIL is located at chromosome 3q26. TRAIL has got 281 amino acid proteins. TRAIL mRNA is expressed at significant levels in most normal tissues. TRAIL binds to the death receptors DR4 (TRAIL-RI) and DR5 (TRAIL-RII) and the receptors DcR1 and DcR2, leading to activation of specific kinases and transcription of genes.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P50592
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Amino acids Y39-N291 from the mouse protein were used as the immunogen for the TRAIL antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
Reconstitution
After reconstitution, the TRAIL antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This TRAIL antibody is available for research use only.
Storage Conditions
After reconstitution, the TRAIL antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the TRAIL antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) mouse Hepa1-6, 2) mouse NIH3T3, 3) rat PC12 and 4) rat NRK cell lysate with TRAIL antibody at 0.5ug/ml. Predicted molecular weight: ~34 kDa (TRAIL), ~20 kDa (soluble TRAIL) .

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