ATF4 Antibody

CAT: 0800-R32586Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-R32586Size:100 µg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ATF4, Activating Transcription Factor 4, is also known as CREB2. ATF4 belongs to the large ATF/CREB family of transcription factors which bind DNA via their basic region and dimerize via their leucine zipper domain to form a variety of homo- and heterodimers to regulate gene transcription. It is identified that members of this family share significant sequence similarity within a leucine zipper DNA-binding motif and an adjacent basic region. The ATF4 gene is mapped to chromosome 22. Unlike CREB, which activates transcription from CRE-containing promoters, CREB2 functions as a specific repressor of CRE-dependent transcription. The transcriptional repressor activity resides within the C-terminal leucine zipper and basic domain region of the CREB2 protein.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
Gene ID
468
UniProt
P18848
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids 71-100 (SNNSKEDAFSGTDWMLEKMDLKEFDLDALL-human) were used as the immunogen for the ATF4 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the ATF4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This ATF4 antibody is available for research use only.
Storage Conditions
After reconstitution, the ATF4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the ATF4 antibody should be determined by the researcher.
Image Legend
Western blot testing of human 1) U-2 OS and 2) SW620 cell lysate with ATF4 antibody at 0.5ug/ml. Predicted molecular weight ~39 kDa.
Product Datasheet
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