KCNQ1 Antibody

KCNQ1 Antibody

• Description: Kv7.1 (KvLQT1) is a potassium channel protein whose primary subunit in humans is encoded by the KCNQ1 gene. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. And this gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene.
• CAS Number: 9007-83-4
• UniProt: P51787
• Host: Rabbit
• Immunogen: Amino acids 356-397 (QQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIR-human) were used as the immunogen for the KCNQ1 antibody.
• Clonality: Polyclonal
• Isotype: IgG
• Applications: WB, IHC-P, IF, FACS
• Format: Antigen affinity purified
• Buffer: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Reconstitution: After reconstitution, the KCNQ1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
• Limitations: This antibody is available for research use only.