Products for Research Use Only
RegisterLogin

GP78 Antibody / AMFR

CAT: 0800-R32507Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-R32507Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Autocrine motility factor receptor, isoform 2, also called GP78, is a protein that in humans is encoded by the AMFR gene. Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. The protein encoded by this gene is a glycosylated transmembrane protein and a receptor for autocrine motility factor. The receptor, which shows some sequence similarity to tumor protein p53, is localized to the leading and trailing edges of carcinoma cells. Its ligand, autocrine motility factor, is a tumor motility-stimulating protein secreted by tumor cells. The encoded receptor is also a member of the E3 ubiquitin ligase family of proteins. It catalyzes ubiquitination and endoplasmic reticulum-associated degradation of specific proteins.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL, Flow cytometry: 1-3ug/million cells, Immunofluorescence: 5 µg/mL
UniProt
Q9UKV5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids E553-S643 from the human protein were used as the immunogen for the GP78 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, FACS, IF
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the GP78 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This GP78 antibody is available for research use only.
Storage Conditions
After reconstitution, the GP78 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Differences in protocols and secondary/substrate sensitivity may require the GP78 antibody to be titrated for optimal performance.
Image Legend
Immunofluorescent staining of FFPE human T-47D cells with GP78 antibody (green) and DAPI nuclear stain (blue) . HIER: steam section in pH6 citrate buffer for 20 min.

UniProtKB · Q9UKV5

E3 ubiquitin-protein ligase AMFR

AMFR_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UKV5
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
AMFR
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.3.2.36
Processing
—
Secondary accessions
P26442, Q8IZ70
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Disease

Disease variantHereditary spastic paraplegiaNeurodegeneration

Cellular component

Endoplasmic reticulumMembrane

PTM

LipoproteinPalmitatePhosphoprotein

Ligand

Metal-bindingZinc

Molecular function

ReceptorTransferase

Domain

TransmembraneTransmembrane helixZinc-finger

Biological process

Ubl conjugation pathwayWnt signaling pathway
Product Datasheet
Loading...

Related Products

CatalogName
F40060-0.4MLAMFR Antibody
F40060-0.08MLAMFR Antibody
RQ4624NONO Antibody / p54nrb Antibody
F53952-0.2MLAntibody
F53952-0.05MLAntibody
F53954-0.05MLAntibody
F53954-0.2MLAntibody
V8674SAF-100UGInhibin alpha Antibody / INHA antibody
V8674-100UGInhibin alpha Antibody / INHA antibody
V8674-20UGInhibin alpha Antibody / INHA antibody

Alternative Products

CatalogName
NBP1-54916Rabbit Polyclonal AMFR/gp78 Antibody
NBP2-97986APCRabbit Polyclonal AMFR/gp78 Antibody [Allophycocyanin]
NBP1-49986PCPRabbit Polyclonal AMFR/gp78 Antibody [PerCP]
NBP2-97986HRabbit Polyclonal AMFR/gp78 Antibody [HRP]
NBP1-49986PERabbit Polyclonal AMFR/gp78 Antibody [PE]
H00000267-M01Mouse Monoclonal AMFR/gp78 Antibody (3D9)
NBP2-97986BRabbit Polyclonal AMFR/gp78 Antibody [Biotin]
NBP1-49986FRabbit Polyclonal AMFR/gp78 Antibody [FITC]
NBP1-49986GRabbit Polyclonal AMFR/gp78 Antibody [DyLight 488]
NBP2-97986CRabbit Polyclonal AMFR/gp78 Antibody [DyLight 650]

Popular Products