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ALDH1B1 Antibody

CAT: 0800-R32505Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32505Size:100 µg
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Description
Aldehyde dehydrogenase X, mitochondrial is an enzyme that in humans is encoded by the ALDH1B1 gene. This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence (FFPE) : 5 µg/mL, Flow cytometry: 1-3ug/million cells
UniProt
P30837
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Amino acids 116-156 (RVYLASLETLDNGKPFQESYALDLDEVIKVYRYFAGWADKW from the human protein were used as the immunogen for the ALDH1B1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, FACS
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the ALDH1B1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This ALDH1B1 antibody is available for research use only.
Storage Conditions
After reconstitution, the ALDH1B1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Differences in protocols and secondary/substrate sensitivity may require the ALDH1B1 antibody to be titrated for optimal performance.
Location
Cytoplasmic, granular
Image Legend
Western blot testing of 1) rat liver, 2) rat testis, 3) rat RH35, 4) mouse brain and 5) mouse liver tissue lysate with ALDH1B1 antibody. Predicted molecular weight ~57 kDa.

UniProtKB · P30837

Aldehyde dehydrogenase family 1 member B1, mitochondrial

AL1B1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P30837
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ALDH1B1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.2.1.28, 1.2.1.3, 1.2.1.36
Processing
Precursor
Secondary accessions
B2R8F0, Q8WX76, Q9BV45
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

Acetylation

Cellular component

Mitochondrion

Ligand

NAD

Molecular function

Oxidoreductase

Domain

Transit peptide
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