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ZWINT Antibody

CAT: 0800-R32455Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32455Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ZW10 interactor (Zwint-1) is a protein that in humans is encoded by the ZWINT gene. This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 1-2 µg/mL
UniProt
O95229
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids Q29-Q249 from the human protein were used as the immunogen for the ZWINT antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
Prior to reconstitution, store at 4oC. After reconstitution, the ZWINT antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This ZWINT antibody is available for research use only.
Storage Conditions
Prior to reconstitution, store at 4°C. After reconstitution, the ZWINT antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the ZWINT antibody should be determined by the researcher.
Image Legend
Western blot testing of rat skeletal muscle lysate with ZWINT antibody at 0.5ug/ml. Expected molecular weight ~31 kDa.

UniProtKB · O95229

Outer kinetochore KNL1 complex subunit ZWINT

ZWINT_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O95229
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ZWINT
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A6NNV6, Q0D2I3, Q9BWD0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cell cycleCell divisionMitosis

Cellular component

CentromereChromosomeKinetochoreNucleus

Domain

Coiled coil
Product Datasheet
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