SNAI3 Antibody

CAT: 0800-R32257Size: 100 µgDry Ice: NoHazardous: No

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CAT#:0800-R32257Size:100 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

SNAI3 is a member of the SNAIL gene family, named for the Drosophila snail gene, which plays roles in mesodermal formation during embryogenesis. SNAI3 gene, was located between KIAA0233 gene and CBFA2T3 gene in human chromosome 16q24.3, a region affected in breast cancer, gastric cancer, hepatocellular carcinoma, ovarian cancer, and therapy-related myeloid leukemia with t (16;21) (q24; q22) translocation. Human SNAI3 gene was found to encode 292-amino-acid polypeptide with the N-terminal SNAG domain and five zinc finger domains. And human SNAI3 mRNA was expressed in skin melanotic melanoma, lung epidermoid carcinoma, and germ cell tumor. Because SNAG zinc-finger proteins are transcriptional repressors implicated in carcinogenesis and embryogenesis, SNAI3 gene might be a potent target of pharmacogenomics in the field of oncology and regenerative medicine.

CAS Number

9007-83-4

Specifications

Western blot: 0.1-0.5 µg/mL

UniProt

Q3KNW1

Host

Rabbit

Reactivity

Human

Immunogen

Amino acids FHCHKPYHTLAGLARHRQLHCHLQ of human SNAI3 were used as the immunogen for the SNAI3 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide

Reconstitution

After reconstitution, the SNAI3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This SNAI3 antibody is available for research use only.

Storage Conditions

After reconstitution, the SNAI3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the SNAI3 antibody should be determined by the researcher.

Image Legend

Western blot testing of human MCF7 cell lysate with SNAI3 antibody. Expected/observed molecular weight ~32 kDa.

UniProtKB · Q3KNW1

Zinc finger protein SNAI3

SNAI3_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q3KNW1
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: SNAI3
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: Q86SU5

Protein keywords

Molecular function

DNA-bindingRepressor

Ligand

Metal-bindingZinc

Cellular component

Nucleus

Technical term

Proteomics identificationReference proteome

Domain

RepeatZinc-finger

Biological process

TranscriptionTranscription regulation

Product Datasheet

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Alternative Products

Catalog	Name
C46327-01	SNAI3 Antibody
A14278	Anti-Zinc finger protein SNAI3 SNAI3 Antibody
MBS8572432-01	SNAI3 Polyclonal Antibody
MBS177967-01	Anti-SNAI3 Antibody
334943-01	SNAI3