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SFRS3 Antibody

CAT: 0800-R32173Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32173Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Splicing factor, arginine/serine-rich 3, also known as SRSF3, is a protein that in humans is encoded by the SFRS3 gene. The protein encoded by this gene is a member of the serine/ arginine (SR) -rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants, one protein-coding and the other non-coding, have been found for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunofluorescence: 5 µg/mL
UniProt
P84103
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids MHRDSCPLDCKVYVGNLGNNGNKTELERA of human SFRS3 were used as the immunogen for the SFRS3 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IF
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the SFRS3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This SFRS3 antibody is available for research use only.
Storage Conditions
After reconstitution, the SFRS3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the SFRS3 antibody should be determined by the researcher.
Location
Nuclear, cytoplasmic
Image Legend
Immunofluorescent staining of FFPE human A549 cells with SFRS3 antibody (green) and Beta Tubulin mAb (red) . HIER: steam section in pH6 citrate buffer for 20 min.

UniProtKB · P84103

Serine/arginine-rich splicing factor 3

SRSF3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P84103
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SRSF3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B4E241, O08831, P23152, Q5R3K0
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

Biological process

mRNA processingmRNA splicingmRNA transportTransport

Domain

Repeat

Molecular function

RNA-binding

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