Products for Research Use Only
RegisterLogin

RAP1A Antibody / KREV1

CAT: 0800-R32160Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-R32160Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Ras-related protein Rap-1A is a protein that in humans is encoded by the RAP1A gene. This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. And it is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs) . The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. Additionally, the encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL
UniProt
P62834
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids EIFYDLVRQINRKTPVEKKKPKKKSC of human Ras-related protein Rap-1A were used as the immunogen for the RAP1A antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the RAP1A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This RAP1A antibody is available for research use only.
Storage Conditions
After reconstitution, the RAP1A antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the RAP1A antibody should be determined by the researcher.
Image Legend
Western blot testing of rat 1) heart, 2) lung, 3) stomach, 4) kidney and mouse 5) heart, 6) lung, 7) stomach and 8) kidney lysate with RAP1A antibody. Expected molecular weight ~21 kDa.

UniProtKB · P62834

Ras-related protein Rap-1A

RAP1A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P62834
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RAP1A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.6.5.2
Processing
Precursor
Secondary accessions
P10113
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Cellular component

Cell junctionCell membraneCytoplasmEndosomeMembrane

Ligand

GTP-bindingNucleotide-binding

Molecular function

Hydrolase

PTM

LipoproteinMethylationPrenylation

Biological process

Neurogenesis

Disease

Tumor suppressor
Product Datasheet
Loading...

Related Products

CatalogName
R34072-100UGRAP1 Antibody
RQ7785RAP1GAP Antibody / Rap1 GTPase-activating protein 1
RQ4624NONO Antibody / p54nrb Antibody
F53954-0.05MLAntibody
F53954-0.2MLAntibody
F53952-0.2MLAntibody
F53952-0.05MLAntibody
V8674-20UGInhibin alpha Antibody / INHA antibody
V8674SAF-100UGInhibin alpha Antibody / INHA antibody
V8674-100UGInhibin alpha Antibody / INHA antibody

Alternative Products

CatalogName
MBS6434957-01RAP1A (Ras-related Protein Rap-1A, KREV-1, KREV1, RAP1, SMGP21) (Biotin)
MBS6434955-01RAP1A (Ras-related Protein Rap-1A, KREV-1, KREV1, RAP1, SMGP21) (AP)
MBS6434965-01RAP1A (Ras-related Protein Rap-1A, KREV-1, KREV1, RAP1, SMGP21) (PE)
MBS6434959-01RAP1A (Ras-related Protein Rap-1A, KREV-1, KREV1, RAP1, SMGP21) (HRP)
MBS6434958-01RAP1A (Ras-related Protein Rap-1A, KREV-1, KREV1, RAP1, SMGP21) (FITC)
MBS6434956-01RAP1A (Ras-related Protein Rap-1A, KREV-1, KREV1, RAP1, SMGP21) (APC)
213009-01RAP1A (Ras-related Protein Rap-1A, KREV-1, KREV1, RAP1, SMGP21) discontinued
MBS6434960-01RAP1A (Ras-related Protein Rap-1A, KREV-1, KREV1, RAP1, SMGP21) (MaxLight 405)
MBS6434964-01RAP1A (Ras-related Protein Rap-1A, KREV-1, KREV1, RAP1, SMGP21) (MaxLight 750)
MBS6434962-01RAP1A (Ras-related Protein Rap-1A, KREV-1, KREV1, RAP1, SMGP21) (MaxLight 550)

Popular Products