SLC19A1 Antibody

• Description:

  Solute carrier family 19 (folate transporter), member 1, also known as SLC19A1 or RFC1, is a protein which in humans is encoded by the SLC19A1 gene. Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. And RFC1 plays a role in maintaining intracellular concentrations of folate.

• Specifications:

  Western blot: 0.5-1 µg/mL

• UniProt:

  P41440

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Monkey

• Immunogen:

  Amino acids FLKRPKRSLFFNRDDRGRCETSASELERMN of human SLC19A1 were used as the immunogen for the SLC19A1 antibody.

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  WB

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide

• Reconstitution:

  After reconstitution, the SLC19A1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

• Limitations:

  This SLC19A1 antibody is available for research use only.

• Storage Conditions:

  After reconstitution, the SLC19A1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

• Formulation:

  0.5 mg/mL if reconstituted with 0.2ml sterile DI water

• Applications Notes:

  Optimal dilution of the SLC19A1 antibody should be determined by the researcher.

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot testing of 1) rat brain, 2) rat ovary, 3) mouse brain, 4) mouse testis, 5) mouse ovary, 6) mouse NIH3T3, 7) human placenta, 8) human HEK293, 9) monkey COS-7, 10) human PC-3, 11) human 22RV1 and 12) human K562 lysate with SLC19A1 antibody. Predicted molecular weight ~65 kDa.