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CTGF Antibody

CAT: 0800-R32048Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32048Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN intercellular signaling protein) . CTGF has important roles in many biological processes, including cell adhesion, migration, proliferation, angiogenesis, skeletal development, and tissue wound repair, and is critically involved in fibrotic disease and several forms of cancers. The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. And the encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
UniProt
P29279
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Amino acids 58-349 of human CTGF were used as the immunogen for the CTGF antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the CTGF antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This CTGF antibody is available for research use only.
Storage Conditions
After reconstitution, the CTGF antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the CTGF antibody should be determined by the researcher.
Location
Cytoplasmic, secreted
Image Legend
Western blot testing of 1) rat liver, 2) rat thymus and 3) human HeLa lysate with CTGF antibody. Predicted/observed molecular weight ~38 kDa.
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