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EDNRB Antibody

CAT: 0800-R32027Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32027Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Endothelin receptor type B, also known as ETB, is a protein that in humans is encoded by the EDNRB gene. The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL, Immunohistochemistry (FFPE) : 0.5-1 µg/mL, Immunofluorescence (FFPE) : 2-4 µg/mL, Flow cytometry: 1-3ug/million cells
UniProt
P24530
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids QSFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKY of human EDNRB were used as the immunogen for the EDNRB antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, FACS
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the EDNRB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This EDNRB antibody is available for research use only.
Storage Conditions
After reconstitution, the EDNRB antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the EDNRB antibody should be determined by the researcher.
Location
Cytoplasmic, membrane
Image Legend
Immunofluorescent staining of FFPE human A431 cells with EDNRB antibody (red) and DAPI nuclear stain (blue) . HIER: steam section in pH6 citrate buffer for 20 min.

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