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IL2RB Antibody

CAT: 0800-R31980Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31980Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IL2RB (INTERLEUKIN 2 RECEPTOR, BETA), also called CD122, is a protein that in humans is encoded by the IL2RB gene. The gene represents the beta subunit and is a type I membrane protein. IL2RB is mapped to 22q12.3. The IL2RB gene contains 10 exons spanning about 24.3 kb and that the gene product is encoded by exons 2-10. The IL2 receptor is present in 3 forms with respect to binding ability to IL2: high, intermediate, and low affinity forms. Analysis of mutants of the beta chain of the IL2 receptor reveals that the granulocyte and monocyte differentiation signals are triggered by different cytoplasmic domains, showing that the signaling pathways responsible for these unique developmental outcomes are separable.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL
UniProt
P16297
Host
Rabbit
Reactivity
Mouse
Immunogen
Amino acids NLHGQDQDRGQGPILTLNTDAYLSLQELQAQDSVHLI of mouse IL2RB were used as the immunogen for the IL2RB antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the IL2RB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This IL2RB antibody is available for research use only.
Storage Conditions
After reconstitution, the IL2RB antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the IL2RB antibody should be determined by the researcher.
Image Legend
Western blot testing of mouse 1) lung, 2) spleen, 3) testis lysate with IL2RB antibody. Expected molecular weight ~61 kDa (unmodified), 70-75 kDa (glycosylated) .

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GTR18234624-01IL2RB Antibody

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