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ARSA Antibody

CAT: 0800-R31971Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31971Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Arylsulfatase A (ARSA) is an enzyme that breaks down sulfatides, namely cerebroside 3-sulfate intocerebroside and sulfate. In humans, arylsulfatase A is encoded by the ARSA gene. ARSA is mapped to 22q13.33. The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL, IHC (FFPE) : 0.5-1 µg/mL, FACS: 1-3ug/10^6 cells, IF/ICC (FFPE) : 2-4 µg/mL
UniProt
P15289
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids QALKQLQLLKAQLDAAVTFGPSQVARGED of human ARSA were used as the immunogen for the ARSA antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, FACS, IF/ICC
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the ARSA antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This ARSA antibody is available for research use only.
Storage Conditions
After reconstitution, the ARSA antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the ARSA antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
Western blot testing of 1) rat testis, 2) rat pancreas, 3) rat skeletal muscle, 4) mouse kidney and 5) human MCF7 lysate with ARSA antibody. Expected molecular weight: 53-63 kDa.

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