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Csf-1 Antibody

CAT: 0800-R31901Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31901Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Macrophage Colony Stimulating Factor 1, also called MCSF or CSF1, is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival ofmonocytes, macrophages, and bone marrow progenitor cells. MCSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of MCSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor (CSF1R or MCSFR encoded by the c-fms proto-oncogene), MCSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.
CAS Number
9007-83-4
Specifications
IHC (FFPE) : 0.5-1 µg/mL, ELISA: 0.1-0.5 µg/mL (mouse protein tested) ; request BSA-free format for coating
UniProt
P07141
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Amino acids 33-262 of mouse Colony stimulating factor 1 were used as the immunogen for the Csf-1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
IHC-P, ELISA (protein)
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the Csf-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Csf-1 antibody is available for research use only.
Storage Conditions
After reconstitution, the Csf-1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Csf-1 antibody should be determined by the researcher.
Location
Cytoplasmic, membrane
Image Legend
IHC testing of FFPE mouse spleen with Csf-1 antibody. HIER: Boil the paraffin sections in pH 6, 10mM citrate buffer for 20 minutes and allow to cool prior to staining.

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