BAG2 Antibody

CAT: 0800-R31849Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-R31849Size:100 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
BAG family molecular chaperone regulator 2 is a protein that in humans is encoded by the BAG2 gene. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. The functional antagonisms displayed between BAG family proteins and Hip suggest that a proper balance of these 2 types of protein is required for achieving optimal cycles of substrate binding and release required for inducting conformational changes in proteins, with Hip promoting peptide substrate binding by Hsc70/Hsp70 and BAG family proteins promoting dissociation.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunofluorescence (FFPE) : 5 µg/mL, Flow cytometry: 1-3ug/million cells
UniProt
O95816
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids 1-211 of human BAG2 were used as the immunogen for the BAG2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IF, FACS
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the BAG2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This BAG2 antibody is available for research use only.
Storage Conditions
After reconstitution, the BAG2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the BAG2 antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
Immunofluorescent staining of FFPE human A431 cells with BAG2 antibody (red) and DAPI nuclear stain (blue) . HIER: steam section in pH6 citrate buffer for 20 min.

Related Products

CatalogName
R31850BAG3 Antibody / BAG family molecular chaperone regulator 3
RQ8326BAG family molecular chaperone regulator 1 Antibody / BAG1
R33549-100UGBAG5 Antibody
R34537-100UGBAG3 Antibody
R31212BAG3 Antibody
R36069-100UGBAG3 Antibody
R32800BAG5 Antibody
RQ4815BAG3 Antibody
R32784BAG1 Antibody
R31213BAG5 Antibody

Alternative Products

CatalogName
ABD7876BAG2 Antibody

Popular Products