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NR2A Antibody

CAT: 0800-R31748Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31748Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
N-methyl-D-aspartate receptor channel, subtype 2A (NMDAR2A or NR2A) is a member of the glutamate-gated ion channel protein family. It is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of NR2A is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Human partial recombinant protein (AA 958-1300) was used as the immunogen for this NR2A antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
The lyophilized NR2A antibody can be stored at 4oC to -20oC. After reconstitution, aliquot and store at -20oC. Avoid repeated freeze/thaws.
Limitations
This NR2A antibody is available for research use only.
Storage Conditions
The lyophilized NR2A antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freeze/thaws.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Variations in secondary/substrate sensitivities and test protocols may require the NR2A antibody to be titrated for optimal performance.
Image Legend
Western blot testing of NR2A antibody and Lane 1: rat brain; 2: mouse brain lysate. Predicted/observed size ~165KD

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