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P2X2 Antibody

CAT: 0800-R31716Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31716Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The P2RX2 gene encodes the P2X2 receptor, which assembles as a trimer to form a ligand-gated ion channel gated by extracellular ATP. P2X2 receptors mediate a variety of cellular responses, including excitatory postsynaptic responses in sensory neurons. The product of this gene belongs to the family of purinoceptors for ATP. P2RX2 is mapped to 12q24.33. It has been found that ATP-activated P2RX2 influenced OHC electromotility, a stimulus-induced change in hair cell length that functions as an amplifier to determine hearing sensitivity and frequency selectivity. Additionally, P2RX2 channels were necessary for development of the temporary threshold shift.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Human partial recombinant protein (AA 139-471) was used as the immunogen for this P2X2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the P2X2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This P2X2 antibody is available for research use only.
Storage Conditions
After reconstitution, the P2X2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the P2X2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic & Membrane
Image Legend
Western blot testing of P2X2 antibody and Lane 1: rat brain; 2: mouse brain; 3: human placenta; 4: (h) HeLa; 5: (h) SHG-44; 6: (m) Neuro-2a; 7: (h) 22RV1; 8: (h) U87 lysate. Expected size 41~55KD
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