Products for Research Use Only
RegisterLogin

Furin Antibody

CAT: 0800-R31596Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-R31596Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Furin (Fur), also known as PACE, is a protein that in humans is encoded by the FURIN gene. The protein encoded by this gene is an enzyme which belongs to the subtilisin-like proprotein convertase family. The gene is located approximately 1 kb upstream of the FES gene on chromosome 15q25-q26. Furin is thought to play a role in tumor progression. It is one of the proteases responsible for the proteolytic cleavage of HIV envelope polyprotein precursor gp160 to gp120 and gp41 prior to viral assembly. Furin is enriched in the Golgi apparatus, where it functions to cleave other proteins into their mature/active forms. Expression in T-cells is required for maintenance of peripheral immune tolerance.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
Host
Rabbit
Reactivity
Human
Immunogen
Human partial recombinant protein (AA 591-794) was used as the immunogen for this Furin antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the Furin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Furin antibody is available for research use only.
Storage Conditions
After reconstitution, the Furin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the Furin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of Furin antibody and Lane 1: HeLa; 2: MCF-7; 3: COLO320; 4: SW620. Observed molecular weight 90~110 kDa (precusor/mature may be glycosylated) .

Related Products

CatalogName
RQ4624NONO Antibody / p54nrb Antibody
F53954-0.05MLAntibody
F53954-0.2MLAntibody
F53952-0.2MLAntibody
F53952-0.05MLAntibody
V8674-20UGInhibin alpha Antibody / INHA antibody
V8674SAF-100UGInhibin alpha Antibody / INHA antibody
V8674-100UGInhibin alpha Antibody / INHA antibody
R20161SAF-250UGLambda Light Chain Antibody / Lambda Antibody
R20179SAF-250UGLambda Light Chain Antibody / Lambda Antibody

Alternative Products

CatalogName
abx100011-01Furin (FURIN) Antibody
abx315737-01Furin (FURIN) Antibody (Biotin)
abx315735-01Furin (FURIN) Antibody (HRP)
abx315736-01Furin (FURIN) Antibody (FITC)
70R-12152Furin antibody
abx616818Furin (FURIN) Peptide

Popular Products