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Kv2.1 Antibody

CAT: 0800-R31536Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31536Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Kv2.1 also called DRK1, is a protein that in humans is encoded by the KCNB1 gene. KCNB1 is found in cardiomyocytes, skeletal muscles, vascular smooth muscles, placental vasculature, retina, and pancreatic beta-cells. It can mediates the voltage-dependent potassium ion permeability of excitable membranes. KCNB1 represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 0.5-1 µg/mL, Immunohistochemistry (Frozen) : 0.5-1 µg/mL
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Human partial recombinant protein (AA 687-858) was used as the immunogen for this Kv2.1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IHC-F
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the Kv2.1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Kv2.1 antibody is available for research use only.
Storage Conditions
After reconstitution, the Kv2.1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the Kv2.1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cell membrane
Image Legend
Western blot testing of Kv2.1 antibody and Lane 1: rat brain; 2: mouse brain. Predicted molecular weight ~96 kDa.
Product Datasheet
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