BDNF Antibody

CAT: 0800-R31503Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-R31503Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Brain-derived neurotrophic factor is a secreted protein that, in humans, is encoded by the BDNF gene. It is a member of the neurotrophin family of growth factors, which are related to the canonical nerve growth factor. BDNF is a prosurvival factor induced by cortical neurons that is necessary for survival of striatal neurons in the brain. It is expressed within peripheral ganglia and is not restricted to neuronal target fields. It has been purified and shown to reduce the amount of naturally occurring neuronal cell death in portions of the peripheral nervous system.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL
UniProt
P23560
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Human partial recombinant protein (AA 129-247) was used as the immunogen for this BDNF antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the BDNF antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This BDNF antibody is available for research use only.
Storage Conditions
After reconstitution, the BDNF antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting points. Titration of the BDNF antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic, secreted
Image Legend
IHC-P staining of mouse brain tissue with BDNF antibody. HIER: steam section in pH8 EDTA buffer for 20 min and allow to cool prior to staining.

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