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Eotaxin Antibody

CAT: 0800-R31494Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31494Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CCL11, also known as Eotaxin, is a potent inducer of eosinophil chemotaxis and is considered as a selective ligand of the CC chemokine receptor 3 (CCR3), which is expressed on eosinophils, basophils, and Th2 lymphocytes. The gene maps to chromosome 17 and is expressed constitutively at high levels in small intestine and colon, and at lower levels in various other tissues. CCL11/Eotaxin is a small cytokine belonging to the CC chemokine family. It is assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. The effects of Eotaxin are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
Host
Rabbit
Reactivity
Mouse
Immunogen
Mouse partial recombinant protein (AA 24-97) was used as the immunogen for this Eotaxin antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the Eotaxin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Eotaxin antibody is available for research use only.
Storage Conditions
After reconstitution, the Eotaxin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the Eotaxin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of Eotaxin antibody (0.5ug/ml) and Lane 1: mouse lung; 2: (m) intestine; 3: (m) HEPA lysate

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