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ST5 Antibody

CAT: 0800-R31411Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31411Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Suppression of tumorigenicity 5 is a protein that in humans is encoded by the ST5 gene. This gene is mapped to 11p15.4. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P78524
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
An amino acid sequence from the middle region of human ST5 (KRHSHDDMLLLAQLSL) was used as the immunogen for this ST5 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the ST5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This ST5 antibody is available for research use only.
Storage Conditions
After reconstitution, the ST5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the ST5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of ST5 antibody and Lane 1: rat testis; 2: human A431; 3: (h) HeLa; 4: (h) COLO320; 5: mouse NIH3T3 lysate. Predicted/observed molecular weight: ~126kDa.

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