CSEN Antibody

• Description :

  Calsenilin (CSEN) is a calcium-dependent transcriptional repressor that is highly expressed in central nervous system, thyroid gland, testis, thymus, and immune cells. The KCNIP3 gene encodes a member of the family of voltage-gated potassium(Kv) channel-interacting proteins, which belong to the neuronal calcium sensor family of proteins. Calsenilin functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. KCNIP3-regulated genes have a critical function in Ig subclass production and proliferation in B lymphocytes. It has been shown to interact with PSEN1 and PSEN2.

• CAS Number :

  9007-83-4

• UniProt :

  Q9Y2W7

• Host :

  Rabbit

• Immunogen :

  An amino acid sequence from the N-terminus of human Calsenilin (MQPAKEVTKASDGSLL) was used as the immunogen for this CSEN antibody.

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  WB

• Format :

  Antigen affinity purified

• Buffer :

  0.5mg/ml if reconstituted with 0.2ml sterile DI water

• Reconstitution :

  After reconstitution, the CSEN antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

• Limitations :

  This CSEN antibody is available for research use only.