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CBG Antibody Cortisol Binding Globulin

CAT: 0800-R31354Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31354Size:100 µg
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Description
Corticosteroid-binding globulin (CBG), also known as Serpin A6 is a protein that in humans is encoded by the SERPINA6 gene. It is mapped 14q32.13. This gene encodes an alpha-globulin protein with corticosteroid-binding properties. CBG is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL, Immunocytochemistry: 0.5-1 µg/mL
UniProt
P08185
Host
Rabbit
Reactivity
Human
Immunogen
An amino acid sequence from the N-terminus of human Cortisol Binding Globulin (ETEIHQGFQHLHQLFAKSD) was used as the immunogen for this CBG antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, ICC
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the CBG antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This CBG antibody is available for research use only.
Storage Conditions
After reconstitution, the CBG antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the CBG antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of CBG antibody and Lane 1: HeLa; 2: A431; 3: U87; 4: 22RV1; 5: PANC cell lysate. Expected/observed size ~45KD

UniProtKB · P08185

Corticosteroid-binding globulin

CBG_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P08185
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SERPINA6
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
CBG
EC number
—
Processing
Precursor
Secondary accessions
A8K456, Q7Z2Q9
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Disease

Disease variant

PTM

Glycoprotein

Ligand

Lipid-bindingSteroid-binding

Cellular component

Secreted

Domain

Signal

Biological process

Transport

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