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SUMO1 Antibody

CAT: 0800-R31344Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31344Size:100 µg
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Description
Small ubiquitin-related modifier 1, also called SMT3C or PIC1 is a protein that in humans is encoded by the SUMO1 gene and a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. SUMO1 is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P63165
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
An amino acid sequence from the N-terminus of human Small ubiquitin-related modifier 1 (DKKEGEYIKLKVIGQD) was used as the immunogen for this SUMO1 antibody (100% homologous in human, mouse and rat) .
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the SUMO1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This SUMO1 antibody is available for research use only.
Storage Conditions
After reconstitution, the SUMO1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the SUMO1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of SUMO1 antibody and Lane 1: rat spleen; 2: human placenta tissue lysate. Predicted molecular weight: 12-15 kDa

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