IRF5 Antibody

CAT: 0800-R31332Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-R31332Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Interferon regulatory factor 5, also called SLEB10, is a protein that in humans is encoded by the IRF5 gene. This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. This gene is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
Q13568
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
An amino acid sequence from the C-terminus of human Interferon regulatory factor 5 (EQFKELHHIWQSQQRLQ) was used as the immunogen for this IRF5 antibody (100% rat homology) .
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the IRF5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This IRF5 antibody is available for research use only.
Storage Conditions
After reconstitution, the IRF5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the IRF5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of IRF5 antibody and Lane 1: human placenta; 2: rat thymus; 3: (r) kidney; 4: (r) ovary tissue lysate. Expected/observed molecular weight ~57kDa.

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